Cardiovascular
 


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Description

Lotrel is a combination of 2 blood pressure medicines, an angiotensin-converting enzyme (ACE) inhibitor and a calcium channel blocker. It works by helping your blood vessels relax (dilate) and lower blood pressure.

Brand name of Lotrel is Lotrel.

Dosage

Lotrel is available in:

10mg + 5mg Standard Dosage

Take Lotrel by mouth with or without food.

Grapefruit and grapefruit juice may increase the risk of side effects from Lotrel. Try to avoid it.

If you want to achieve most effective results do not stop taking Lotrel suddenly.

Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Overdose

If you overdose Lotrel and you don't feel good you should visit your doctor or health care provider immediately.

Side effects

Lotrel has its side effects. The most common are:

dizziness or lightheadedness when sitting or standingheadachepersistentdry coughswelling of the hands or feet

Less common but more serious side effects during taking Lotrel:

allergy reactions (urticaria, breathing difficulties, rash, and eruption)chest paininfection (fever, sore throat)irregular or slow heartbeatyellowing of the skin or eyes

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Contra-indications

Do not take Lotrel if you are allergic to Lotrel components or similar medicines (eg, any other ACE inhibitor).

Do not take Lotrel if you're pregnant or you plan to have a baby, or you are a nursing mother. Lotrel can harm your baby.

Do not take Lotrel if you are using iron dextran by injection.

Take Lotrel with care if you are taking Dextran or sildenafil because the risk of serious side effects, including low blood pressure or severe allergic reactions, may be increased; potassium-sparing diuretics (eg, amiloride) or potassium supplements because the risk of side effects, including high potassium levels resulting in possible irregular heartbeat and stopping of the heart, may be increased; Lithium, sulfonylureas (eg, glipizide), thiazide diuretics (eg, hydrochlorothiazide), thiopurines (eg, azathioprine), or vasopressin receptor antagonists (eg, conivaptan) because they may increase the risk of Lotrel 's side effects; Insulin or oral diabetes medicine (eg, glyburide) because the risk of side effects, including low blood sugar levels (eg, hunger, shakiness or weakness, dizziness, headache, sweating), may be increased by Lotrel.

Be careful with Lotrel if you suffer from or have a history of heart failure, any heart disease, aortic stenosis (an abnormal narrowing of the opening of the aortic valve in the heart), liver or kidney problems, a kidney transplant, or diabetessystemic lupus erythematosus (SLE or lupus), hardening of skin disease (scleroderma), bone marrow suppression, low blood counts, low blood pressure, low blood sodium, high blood potassium, or narrowing or hardening of the arteries of the brain, or if you are dehydrated.

Do not use potassium supplements or salt substitutes.

If you want to achieve most effective results without any side effects it is better to avoid alcohol.

Grapefruit and grapefruit juice may increase the risk of side effects from Lotrel.

Do not stop taking Lotrel suddenly.




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